Long-term TNF-alpha therapy for preserving beta cell function in new onset type 1 diabetes: a case report.
Adya RaoLauren M QuinnParth NarendranPublished in: Clinical diabetes and endocrinology (2024)
Our patient's improvement in glycaemic control can be explained by immunomodulation and C peptide preservation from infliximab. With the growing focus on type 1 diabetes disease modulation and working towards an 'insulin free T1D', our findings strengthen the evidence base for the repurposing of and long-term treatment with anti-TNF-α agents to preserve beta-cell function in new onset T1D.