Comparison of the regenerative effects of bone marrow/adipose-derived stem cells in the Asherman model following local or systemic administration.

Farhad MonsefTayebe ArtimaniZohreh AlizadehMahdi RamazaniGhasem SolgiMahnaz YavangiSara Soleimani Asl

Published in: Journal of assisted reproduction and genetics (2020)

Stem cell transplantation may reconstruct the damaged endometrium, but it is recommended to select the most effective stem cells and injection route. Because the removal of the fibrosis and the replacement of the epithelia cells is an effective therapeutic strategy for AS, in this study, we conclude that the local injection of AMSCs is more appropriate than BMSCs to treat AS.

Keyphrases

stem cell transplantation
stem cells
bone marrow
high dose
mesenchymal stem cells
induced apoptosis
cell therapy
ultrasound guided
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
tissue engineering
drug induced