Resveratrol and quercetin protect from Benzo(a)pyrene-induced autophagy in retinal pigment epithelial cells.

Murat KasikciSerkan Sen

Published in: International ophthalmology (2024)

B(a)p exposure caused autophagy in ARPE-19 cells, but did not induce apoptosis. RES and QR treatments prevented B(a)p-induced autophagy. Therefore, RES and QR treatments showed protective effect against potential degenerative diseases caused by chronic exposure to B(a)p.

Keyphrases

endoplasmic reticulum stress
cell death
induced apoptosis
cell cycle arrest
oxidative stress
diabetic rats
signaling pathway
high glucose
drug induced
pi k akt
endothelial cells
stress induced