Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition.

Leonard Schmiester Fara Brasó-Maristany Blanca Gonzalez-Farre Tomás Pascual Joaquín Gavilá Xavier Tekpli Jürgen Geisler Vessela N Kristensen Arnoldo Frigessi Aleix Prat Alvaro Köhn-Luque

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

A mathematical modeling approach accurately predicts patient outcome following CDK4/6i plus endocrine therapy that marks a step toward more personalized treatments in patients with Luminal B breast cancer.

Keyphrases

cell cycle
cell proliferation
bone marrow
breast cancer risk