Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort.
Mohamad HabesJon B ToledoSusan M ResnickJimit DoshiSandra Van der AuweraGuray ErusDeborah JanowitzK HegenscheidGeorg HomuthHenry VölzkeWolfgang U HoffmannHans Jörgen GrabeChristos DavatzikosPublished in: AJNR. American journal of neuroradiology (2016)
Our study indicates that measurable apolipoprotein E-related brain atrophy does not occur in early adulthood and midlife and suggests that such atrophy may only occur more proximal to the onset of clinical symptoms of dementia.
Keyphrases
- healthcare
- magnetic resonance imaging
- public health
- depressive symptoms
- mild cognitive impairment
- mental health
- risk assessment
- computed tomography
- cognitive decline
- high fat diet
- adipose tissue
- sleep quality
- multiple sclerosis
- contrast enhanced
- blood brain barrier
- cognitive impairment
- white matter
- early life
- cerebral ischemia
- health promotion