Albendazole solution formulation via vesicle-to-micelle transition of phospholipid-surfactant aggregates.
Zahari VinarovGabriela GanchevaVladimir KatevSlavka S TcholakovaPublished in: Drug development and industrial pharmacy (2018)
A new albendazole delivery system with high drug load and low toxicity of the materials used was developed. The high solubility of albendazole was explained with vesicle-to-micelle transition due to the larger interfacial curvature preferred for albendazole solubilization locus.