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The circular RNA expression profile in ovarian serous cystadenocarcinoma reveals a complex circRNA-miRNA regulatory network.

Minhui ZhuangJian ZhaoJing WuShilong FuPing HanXiaofeng Song
Published in: BMC medical genomics (2021)
Our study revealed the circRNA expression profile in the tissues of patients with ovarian serous cystadenocarcinoma. The differential expression of circRNAs was thought to be associated with ovarian serous cystadenocarcinoma in the enrichment analysis, and co-expression analysis with relevant mRNAs and miRNAs illustrated the latent regulatory network. We also constructed a complex circRNA-miRNA interaction network and then demonstrated the potential function of certain circRNAs to aid future diagnosis and treatment.
Keyphrases
  • high grade
  • transcription factor
  • gene expression
  • wastewater treatment
  • current status
  • risk assessment
  • genome wide identification