Exploring the Effects of Temperament on Gray Matter Volume of Frontal Cortex in Patients with Mood Disorders.

Tao Yang Raymond W LamJia HuangYousong SuJing LiuXiaorui YangLu YangNa ZhuGuoqing ZhaoRuizhi MaoRubai ZhouWeiping XiaHongmei LiuZuowei Wang Jun Chen Yi-Ru Fang

Published in: Neuropsychiatric disease and treatment (2021)

Patients with BD and MDD had different temperament characteristics. The prominent temperament subscales in patients with BD were cyclothymia, irritable and hyperthymia. Patients with greater hyperthymia had lower gray matter volume in right frontal gyrus. Temperament may reflect an endophenotype in patients with mood disorders, especially in BD.

Keyphrases

functional connectivity
bipolar disorder
major depressive disorder
working memory
sleep quality