Dietary quality indices modifies the effects of melanocortin-4 receptor (MC4R) rs17782313 polymorphism on cardio-metabolic risk factors and hypothalamic hormones in obese adults.

Mahdieh KhodarahmiHouman KahrobaMohammad Asghari JafarabadiMehran Mesgari-AbbasiMahdieh Abbasalizad Farhangi

Published in: BMC cardiovascular disorders (2020)

Our study showed that MC4R rs17782313 interacts with adherence to the dietary quality indices (HEI and DQI-I) to influence several cardio-metabolic risk factors in obese male and females. Further large prospective studies are warranted to confirm our findings.

Keyphrases

risk factors
adipose tissue
weight loss
metabolic syndrome
type diabetes
obese patients
quality improvement
binding protein
bariatric surgery
insulin resistance