Serum orexin-A levels are associated with disease progression and motor impairment in multiple sclerosis.

Mehmet GencerEce AkbayırMelis ŞenErdil ArsoyVuslat YılmazNesrin BulutErdem TuzunRecai Türkoğlu

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)

Our results suggest that orexin-A levels are decreased in parallel to disease progression and motor system deterioration in the earlier stages of the disease. Thus, orexin-A might be used as a potential biomarker of physical disability.

Keyphrases

multiple sclerosis
white matter