Genomic characterization of non-schistosomiasis-related squamous cell carcinoma of the urinary bladder: A retrospective exploratory study.

Esmail M Al-EzziZachary W VeitchSamer H SalahTheodorus H Van der KwastTracy L StockleyShamini SelvarajahTong ZhangSrikala S SridharAdrian G SacherNazanin Fallah-RadGirish S KulkarniAlexandre R ZlottaAntonio FinelliAaron Richard Hansen

Published in: PloS one (2021)

NSR-SCCUB has potentially actionable genomic alterations with anticancer agents and many of these aberrations are also seen in UC. The recruitment of NSR-SCCUB patients harboring such mutations should be considered in biomarker driven urinary bladder cancer studies.

Keyphrases

squamous cell carcinoma
end stage renal disease
copy number
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
radiation therapy
gene expression
genome wide