Preoperative CT and survival data for patients undergoing resection of colorectal liver metastases.
Amber L SimpsonJacob J PeoplesJohn M CreasyGabor FichtingerNatalie GangaiKrishna Nand Keshava MurthyAndras LassoJinru ShiaMichael I D'AngelicaRichard Kinh Gian DoPublished in: Scientific data (2024)
The liver is a common site for the development of metastases in colorectal cancer. Treatment selection for patients with colorectal liver metastases (CRLM) is difficult; although hepatic resection will cure a minority of CRLM patients, recurrence is common. Reliable preoperative prediction of recurrence could therefore be a valuable tool for physicians in selecting the best candidates for hepatic resection in the treatment of CRLM. It has been hypothesized that evidence for recurrence could be found via quantitative image analysis on preoperative CT imaging of the future liver remnant before resection. To investigate this hypothesis, we have collected preoperative hepatic CT scans, clinicopathologic data, and recurrence/survival data, from a large, single-institution series of patients (n = 197) who underwent hepatic resection of CRLM. For each patient, we also created segmentations of the liver, vessels, tumors, and future liver remnant. The largest of its kind, this dataset is a resource that may aid in the development of quantitative imaging biomarkers and machine learning models for the prediction of post-resection hepatic recurrence of CRLM.
Keyphrases
- patients undergoing
- liver metastases
- free survival
- end stage renal disease
- computed tomography
- high resolution
- machine learning
- ejection fraction
- chronic kidney disease
- electronic health record
- big data
- image quality
- contrast enhanced
- primary care
- prognostic factors
- positron emission tomography
- magnetic resonance
- combination therapy
- patient reported outcomes
- deep learning
- replacement therapy
- data analysis
- pet ct