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Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma.

Avinash GuptaChristopher TowersFrances WillenbrockRoz BrantDarren Richard HodgsonAlan SharpePaul SmithAnthony CuttsAnna SchuhRuth AsherKevin MyersSharon LoveLinda CollinsAdelyn WiseMark Roy MiddletonValentine Moya Macaulay
Published in: British journal of cancer (2019)
DOC-MEK (EudraCT no: 2009-018153-23).
Keyphrases
  • wild type
  • pi k akt
  • skin cancer
  • protein kinase
  • structural basis
  • small molecule