Nephrotoxic drug burden among 1001 critically ill patients: impact on acute kidney injury.
Stephan EhrmannJulie HelmsAurélie JoretLaurent Martin-LefevreJean-Pierre QuenotJean-Etienne HerbrechtDalila Benzekri-LefevreRené RobertArnaud DesachyFréderic BellecGaëtan PlantefeveAnne BretagnolAuguste DargentJean-Claude LacheradeFerhat MezianiBruno GiraudeauElsa TavernierPierre-François Dequinnull nullPublished in: Annals of intensive care (2019)
The frequently observed prescription of nephrotoxic drugs to critically ill patients may be evaluated semi-quantitatively through computing drug.day nephrotoxic burden, an index significantly associated with subsequent AKI occurrence, and worsening among patients with lower severity of disease.