Evaluation of a fully automated high-throughput serology assay for detection of Hepatitis D virus antibodies.

Xiaoxing QiuAbbas HadjiAna OlivoAustin HodgesCarla BeertsenMark AndersonMary RodgersDora MbanyaSusan ElaborotGavin Cloherty

Published in: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (2024)

When compared to the LIASON Anti-HDV test, the ARCHITECT HDV Ig assay demonstrated enhanced sensitivity and specificity and better NPV and PPV values for HDV RNA status. The ARCHITECT HDV Ig assay represents a promising tool for universal screening of all HBsAg-positive persons.

Keyphrases

high throughput
hepatitis b virus
machine learning
structural basis
real time pcr