Cell culture medium supplemented with taurine decreases basic charge variant levels of a monoclonal antibody.

Mengjuan LiuJiaqi WangHongping TangLi FanLiang ZhaoHai-Bin WangYan ZhouWen-Song Tan

Published in: Biotechnology letters (2018)

Taurine exhibits noticeable impact on lower basic charge variants, which are mainly due to the decrease of lysine variant and oxidized protein variants.

Keyphrases

monoclonal antibody
copy number
solar cells
amino acid
protein protein
gene expression
low density lipoprotein