Skin biopsy and quantitative sensory assessment in an Italian cohort of ATTRv patients with polyneuropathy and asymptomatic carriers: possible evidence of early non-length dependent denervation.
Luca LeonardiEleonora GalosiFiammetta VanoliAlessandra FasolinoGiuseppe Di PietroMarco LuigettiMario SabatelliLaura FiondaMatteo GaribaldiGirolamo AlfieriAntonio LaulettaStefania MorinoMarco SalvettiAndrea TruiniGiovanni AntoniniPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
Skin biopsy can disclose an early non-length-dependent small fiber loss in ATTRv-PN and, together with QST, could provide a useful insight disease onset and progression.