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Direct assessment of individual skin barrier components by electrical impedance spectroscopy.

Roman MannweilerSophia BergmannSabine Vidal-Y-SyJohanna M BrandnerDorothee Günzel
Published in: Allergy (2021)
In conclusion, the present technique allows to separately measure the barrier properties of SC and VE and further evaluate the Cldn1 and 4 knockdown impact on the skin barrier. As the measurement with agarose-embedded electrolyte allowed non-invasive identification of the Cldn1 knockdown, this opens the way to detailed in vivo skin barrier assessment.
Keyphrases
  • soft tissue
  • wound healing
  • magnetic resonance
  • computed tomography
  • contrast enhanced