Nanocarriers Used in Drug Delivery to Enhance Immune System in Cancer Therapy.
Giovanna C N B LôboKaren L R PaivaAna Luísa G SilvaMarina Mesquita SimõesMarina A RadicchiSônia Nair BáoPublished in: Pharmaceutics (2021)
Cancer, a group of diseases responsible for the second largest cause of global death, is considered one of the main public health problems today. Despite the advances, there are still difficulties in the development of more efficient cancer therapies and fewer adverse effects for the patients. In this context, nanobiotechnology, a materials science on a nanometric scale specified for biology, has been developing and acquiring prominence for the synthesis of nanocarriers that provide a wide surface area in relation to volume, better drug delivery, and a maximization of therapeutic efficiency. Among these carriers, the ones that stand out are those focused on the activation of the immune system. The literature demonstrates the importance of this system for anticancer therapy, given that the best treatment for this disease also activates the immune system to recognize, track, and destroy all remaining tumor cells.
Keyphrases
- drug delivery
- cancer therapy
- public health
- papillary thyroid
- drug release
- end stage renal disease
- ejection fraction
- mental health
- systematic review
- peritoneal dialysis
- childhood cancer
- lymph node metastasis
- chronic kidney disease
- young adults
- mesenchymal stem cells
- patient reported outcomes
- squamous cell carcinoma
- bone marrow
- patient reported