Absence of early mood improvement as a robust predictor of rTMS nonresponse in major depressive disorder.
Alex M MirmanJuliana CorlierAndrew C WilsonReza TadayonnejadKatharine G MarderChristopher M PlemanDavid E KrantzScott A WilkeJennifer G LevittNathaniel D GinderRashi OjhaZafiris J DaskalakisAndrew F LeuchterJonathan C LeePublished in: Depression and anxiety (2022)
Identifying a lack of early mood improvement is a practical and robust method to predict rTMS nonresponse. This suggests a treatment protocol change may be indicated in patients with more severe baseline depression showing minimal early mood improvement.