Hepatitis E virus genotypes and subgenotypes causing acute hepatitis, Bulgaria, 2013-2015.

Roberto BruniUmbertina VillanoMichele EquestrePaola ChionneElisabetta MadonnaDilyana Trandeva-BankovaMaria Peleva-PishmishevaTencho TenevEleonora CellaMassimo CiccozziGiulio PisaniElitsa Golkocheva-MarkovaAnna Rita Ciccaglione

Published in: PloS one (2018)

Most acute hepatitis E cases in Bulgaria are caused by HEV-3, subtypes 3e, 3f and 3c. Circulation of 3e appears quite different from 3f and 3c, with 3e restricted to the South-West area while 3f and 3c diffused over the country. The factors underlying the observed molecular and geographical differences remain to be investigated.

Keyphrases

liver failure
respiratory failure
aortic dissection
drug induced
hepatitis b virus
intensive care unit