Identification and Validation of Hub Genes in Acute Pancreatitis and Hypertriglyceridemia.

Shiyu ZhangZhihai LiangXuelian XiangLi LiuHuiying YangGuodu Tang

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2022)

Overall, we identified six hub genes associated with AP and two common DEGs associated with AP and hypertriglyceridemia along with seven miRNAs that may regulate AP. This study could provide new ideas for further elucidation of the pathogenesis of hypertriglyceridemia-induced acute pancreatitis in the future.

Keyphrases

bioinformatics analysis
transcription factor
network analysis
high glucose
diabetic rats
gene expression
current status
drug induced
genome wide identification
oxidative stress
endothelial cells