Anthracene Single-Crystal Scintillators for Computer Tomography Scanning.
Mingxi ChenLingjie SunZhongzhu HongHongyun WangYan XiaSi LiuXiaochen RenXiaotao ZhangDongzhi ChiHuang-Hao YangWenping HuPublished in: ACS applied materials & interfaces (2022)
X-ray imaging and computed tomography (CT) technology, as the important non-destructive measurements, can observe internal structures without destroying the detected sample, which are always used in biological diagnosis to detect tumors, pathologies, and bone damages. It is always a challenge to find materials with a low detection limit, a short exposure time, and high resolution to reduce X-ray damage and acquire high-contrast images. Here, we described a low-cost and high-efficient method to prepare centimeter-sized anthracene crystals, which exhibited intense X-ray radioluminescence with a detection limit of ∼0.108 μGy s -1 , which is only one-fifth of the dose typically used for X-ray diagnostics. Additionally, the low absorption reduced the damage in radiation and ensured superior cycle performance. X-ray detectors based on anthracene crystals also exhibited an extremely high resolution of 40 lp mm -1 . The CT scanning and reconstruction of a foam sample were then achieved, and the detailed internal structure could be clearly observed. These indicated that organic crystals are expecting to be leading candidate low-cost materials for low-dose and highly sensitive X-ray detection and CT scanning.
Keyphrases
- high resolution
- dual energy
- computed tomography
- low cost
- electron microscopy
- image quality
- contrast enhanced
- low dose
- mass spectrometry
- positron emission tomography
- oxidative stress
- magnetic resonance imaging
- label free
- tandem mass spectrometry
- room temperature
- high speed
- deep learning
- machine learning
- bone mineral density
- radiation therapy
- quantum dots
- liquid chromatography
- postmenopausal women
- convolutional neural network
- molecularly imprinted
- body composition