Esophageal hypercontractility is abolished by cholinergic blockade.
Arash BabaeiSadaf ShadBenson T MasseyPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
Hypercontractility is cholinergically mediated in all esophageal motor disorders. Most patients with isolated EHC appear to have excessive cholinergic drive, rather than loss of inhibitory innervation, and might be candidates for treatment with anticholinergic agents.