Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD program.

Xuting WangHye-Youn ChoMichelle R CampbellVijayalakshmi PanduriSilvina CovielloMauricio T CaballeroDeepa SambandanSteven R KleebergerFernando P PolackGaston OfmanDouglas A Bell

Published in: Clinical epigenetics (2022)

While results must be interpreted with caution because of the small size of this study, NRBC content strongly impacted DNA methylation profiles in preterm cord blood and EWAS analysis revealed potential insights into biological pathways involved in BPD pathogenesis.

Keyphrases

dna methylation
preterm infants
cord blood
low birth weight
gene expression
genome wide
small molecule
quality improvement
high throughput
single cell
climate change
copy number
human health