Autism spectrum disorder in young patients with congenital central hypoventilation syndrome: role of the autonomic nervous system dysfunction.

Benjamin DudoignonAnna MaruaniRichard DelormeMaxime PatoutMylene FefeuPierre EllulPlamen BokovChristophe Delclaux

Published in: Orphanet journal of rare diseases (2024)

Our study suggests a high prevalence of ASD in patients with CCHS. Glycemic dysfunction and longer initial hospitalization stays were associated with ASD development. A defect in parasympathetic modulation was associated with worse adaptative functioning.

Keyphrases

autism spectrum disorder
attention deficit hyperactivity disorder
intellectual disability
heart rate variability
oxidative stress
type diabetes
heart rate
case report
middle aged
skeletal muscle
weight loss
positive airway pressure
sleep apnea