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Clinical spectrum and prognostic value of TP53 mutations in circulating tumor DNA from breast cancer patients in China.

Zongbi YiZongbi YiGuohua RongYanfang GuanChunxiao LiBing-He Xu
Published in: Cancer communications (London, England) (2020)
TP53 mutations in exons 5-8 may be an independent prognostic marker for short DFS in patients with metastatic breast cancer. TP53 mutations had opposite effects on trastuzumab-treated patients treated with and without taxanes.
Keyphrases
  • circulating tumor
  • metastatic breast cancer
  • cell free
  • circulating tumor cells
  • single molecule