Clinical Burden of Chronic Obstructive Pulmonary Disease in Patients with Suboptimal Peak Inspiratory Flow.
Jill A OharDonald A MahlerGabrielle N DavisDavid A LombardiEdmund J MoranGlenn D CraterPublished in: Canadian respiratory journal (2024)
In these trials, participants with COPD who had sPIF against the medium-low resistance DPIs had more dyspnea and worse health status than those with oPIF. These results demonstrate that sPIF is associated with a higher clinical burden as measured by patient-reported outcomes.