'Evaluation of adverse prognostic gene alterations & MRD positivity in BCR::ABL1-like B-lineage acute lymphoblastic leukaemia patients, in a resource-constrained setting.
Dikshat Gopal GuptaNeelam VarmaSreejesh SreedharanunniSarki Abba AbdulkadirShano NaseemMan Updesh Singh SachdevaJogeshwar BinotaParveen BosePankaj MalhotraAlka KhadwalSubhash VarmaPublished in: British journal of cancer (2023)
With this practical approach, we reported a high incidence of BCR::ABL1-like ALLs, and a lower frequency of CRLF2 alteration & associated CGFs. Recognising this entity, early at diagnosis is crucial to optimise personalised treatment strategies.
Keyphrases
- tyrosine kinase
- chronic myeloid leukemia
- acute lymphoblastic leukemia
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- liver failure
- risk factors
- prognostic factors
- genome wide
- dna methylation
- single cell
- respiratory failure
- electronic health record
- adverse drug
- genome wide identification