Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow's milk allergy.
Ellen De PaepeVera PlekhovaPablo VangeenderhuysenNele BaeckDominique BullensTania ClaeysMarilyn De GraeveKristien KamoenAnneleen NotebaertTom Van de WieleWim Van Den BroeckKoen VanledeMyriam Van WinckelLars VereeckeChris ElliottEric CoxLynn VanhaeckePublished in: Allergy (2024)
Our results indicate that gut dysbiosis precedes allergic inflammation and nurtures a chronic low-grade inflammation in children on elimination diets, opening important new opportunities for future prevention and treatment strategies.