Mesenchymal stem cells reduce ER stress via PERK-Nrf2 pathway in an aged mouse model.

Eun Joo LeeNayra CárdenesDiana ÁlvarezJacobo SellarésJohn SembratPaola ArandaYating PengJordan BullockSeyed M NouraieAna L MoraMauricio Rojas

Published in: Respirology (Carlton, Vic.) (2019)

Our data suggest that MSC operate on ER stress via several pathways, but the PERK-Nrf2 pathway revealed to be the main functioning pathway in our bleomycin model.

Keyphrases

mesenchymal stem cells
mouse model
oxidative stress
endoplasmic reticulum stress
single cell
electronic health record
bone marrow
stem cells
endoplasmic reticulum
deep learning