The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients.
Anne M SchijvensFransje H S van HesterenElisabeth A M CornelissenCharlotte M H H T Bootsma-RobroeksRoger J M BrüggemannDavid M BurgerSaskia N de WildtMichiel F SchreuderRob Ter HeinePublished in: Pediatric nephrology (Berlin, Germany) (2018)
A critical role for hematocrit in therapeutic drug monitoring of tacrolimus in pediatric kidney transplant patients is suggested in this study. Therefore, we believe that hematocrit correction could be a step towards improvement of tacrolimus dose individualization.