Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states.

Roberta Nicoleta BogoiAlicia de PabloEulalia ValenciaLuz Martín-CarboneroVictoria MorenoHelem Haydee Vilchez-RuedaVictor AsensiRosa RodriguezVictor ToledanoBerta Rodés

Published in: Clinical epigenetics (2018)

The current study shows an increase in chromatin-modifying enzymes and remodelers and in global DNA methylation in patients with chronic HIV-1 infection, modulated by various levels of viral control and progression.

Keyphrases

genome wide
dna methylation
antiretroviral therapy
gene expression
hiv infected
hiv positive
human immunodeficiency virus
dna damage
hiv aids
transcription factor
copy number
hepatitis c virus
hiv testing
men who have sex with men
genome wide identification