Placenta mediates the effect of maternal hypertension polygenic score on offspring birth weight: a study of birth cohort with fetal growth velocity data.

Noriko SatoAyako FudonoChihiro ImaiHidemi TakimotoIori TaruiTomoko AoyamaSatoshi YagoMotoko OkamitsuShuki MizutaniNaoyuki Miyasaka

Published in: BMC medicine (2021)

Our study suggests that maternal hypertension genes are strongly associated with placental growth and that fetal growth inhibition is induced through the intrauterine environment established by the placenta.

Keyphrases

birth weight
gestational age
blood pressure
weight gain
high fat diet
pregnant women
electronic health record
diabetic rats
skeletal muscle
machine learning
artificial intelligence