Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis.

Hanne Van Der HeijdenBenoit FatouDiana SibaiKacie HoytMaria TaylorKin CheungJordan LemmeMariesa CayBenjamin GoodlettJeffery LoMelissa M HazenOlha HalyabarEsra MeidanRudy SchreiberCamilo JaimesKirsten EcklundLauren A HendersonMargaret H ChangPeter A NigrovicRobert P SundelHanno SteenJaymin Upadhyay

Published in: Pediatric rheumatology online journal (2022)

The current proteomic findings suggest both inflammatory- and non-inflammatory mediated mechanisms as potential factors associated with JIA pain. Validation of these preliminary observations using larger patient cohorts and a longitudinal study design may further point to novel serologic markers of pain in JIA.

Keyphrases

juvenile idiopathic arthritis
chronic pain
pain management
neuropathic pain
oxidative stress
disease activity
spinal cord injury
spinal cord
risk assessment
sars cov
label free
climate change