Urinary complement proteins and risk of end-stage renal disease: quantitative urinary proteomics in patients with type 2 diabetes and biopsy-proven diabetic nephropathy.

L ZhaoY ZhangFang LiuH YangY ZhongY WangS LiQ SuL TangL BaiH RenY ZouS WangS ZhengH XuL LiJ ZhangZ ChaiM E CooperN Tong

Published in: Journal of endocrinological investigation (2021)

Urinary abundance of complement proteins was significantly associated with ESRD in patients with T2DM and biopsy-proven DN, indicating that therapeutically targeting the complement pathway may alleviate progression of DN.

Keyphrases

end stage renal disease
chronic kidney disease
diabetic nephropathy
peritoneal dialysis
ultrasound guided
fine needle aspiration
high resolution
cancer therapy
type diabetes
skeletal muscle
drug delivery
weight loss
label free