Prognostic Significance of Adjuvant Chemotherapy Induced Amenorrhea in Luminal A and B Subtypes.
Çetin OrduKezban Nur PilancıTuba Kayan TapanFiliz ElbükenÜlkühan İner KöksalAhmet Serkan IlgunDauren SarsenovAyşe Esra AydınAlper OztürkZeynep İyigün ErdoğanFiliz AğaçayakFatmagül ÇubukCoşkun TecimerYeşim EralpTomris DuymazFatma AktepeVahit ÖzmenPublished in: European journal of breast health (2018)
As a conclusion; survival advantage of the chemotherapy induced amenorrhea more pronounced with hormone receptor positivity, lymph node involvement, and advanced disease over patients who do not develop amenorrhea. This advantage of amenorrhea development further prolongs survival compared with luminal B in the luminal A molecular subtype.