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Epigenetic regulation of osteogenic differentiation of periodontal ligament stem cells in periodontitis.

Jingwei CaoQiong ZhangQiyuan YangYue YuMingmei MengJing Zou
Published in: Oral diseases (2022)
Epigenetics of osteogenic differentiation of PDLSCs in inflammation exhibits the contrary effect compared to a non-inflammatory environment. The application of epigenetic drugs to regulate the abnormal epigenetic status in periodontitis and focus on alveolar bone regeneration is promising.
Keyphrases
  • bone regeneration
  • stem cells
  • dna methylation
  • oxidative stress
  • gene expression
  • cell therapy
  • bone marrow
  • mesenchymal stem cells