Investigating the impact of botulinum toxin type a on the migration of normal human dermal fibroblasts: An in vitro wound healing assay.

Wilai Thanasarnaksorn Cherrin PomsoongPhongthon KanjanasiriratKedchin JearawuttanakulSuparerk BorwornpinyoSuradej HongengYanisa RatanapokasatitTeerapong Rattananukrom

Published in: Journal of cosmetic dermatology (2024)

Different types and dilutions of BoNT-A demonstrated variable inhibitory effects on NHDF migration in vitro. The selection of BoNT-A formulation may significantly impact the clinical outcome of scar prevention related to fibroblast migration.

Keyphrases

wound healing
botulinum toxin
endothelial cells
drug delivery
high throughput
extracellular matrix
induced pluripotent stem cells