Neuroinflammation and Microglial Activation at Rostral Ventrolateral Medulla Underpin Cadmium-Induced Cardiovascular Dysregulation in Rats.

Ching-Yi TsaiChi FangJacqueline C C WuChiung-Ju WuKuang-Yu DaiShu-Mi Chen

Published in: Journal of inflammation research (2021)

Based on these biochemical, pharmacological and morphological observations, we conclude that neuroinflammation and microglial activation at RVLM, and their downstream cellular mechanisms, causally underpin cadmium-induced cardiovascular dysregulation.

Keyphrases

lipopolysaccharide induced
lps induced
high glucose
inflammatory response
diabetic rats
traumatic brain injury
heavy metals
drug induced
neuropathic pain
risk assessment