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Differential Analysis of Serum Principal Components Treated with Compound Sophora Decoction and Related Compounds Based on High-Resolution Mass Spectrometry (HRMS).

Wanjin SunJunjie ZhangConghui ZhouBin YanQuan CaiHongxia HeXueyun DuanHeng Fan
Published in: Evidence-based complementary and alternative medicine : eCAM (2020)
By comparing the differences in the serum principal components from each administration group, we found that the FFKST group exhibited enhanced synthesis of the serum principal components; however, the compound doses of matrine and oxymatrine monomers did not exhibit the same changes in the serum principal components of UC-induced rats. Finally, the traditional Chinese medicine compound is more advantageous than monomers.
Keyphrases
  • high resolution mass spectrometry
  • liquid chromatography
  • high glucose
  • ultra high performance liquid chromatography