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SERPINA1 and MAN1B1 polymorphisms are not linked to severe liver disease in a French cohort of alpha-1 antitrypsin deficiency children.

Philippe JolyAlain LachauxMathias RuizLioara RestierAbdelhouaed BelmalihColette Chapuis-CellierAlain FrancinaCéline RenouxMarion Bouchecareilh
Published in: Liver international : official journal of the International Association for the Study of the Liver (2017)
We conclude that genetic polymorphisms in these two genes probably do not influence the onset of severe liver disease in A1ATD.
Keyphrases
  • early onset
  • genome wide
  • drug induced
  • dna methylation
  • transcription factor