Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.

Luz Dary Castañeda-CastañedaMauricio GamboaJohn A NovaLeonardo PulidoJose D Tovar-Parra

Published in: BioMed research international (2020)

Differences in histological subtypes and mutations in the BRAF, NRAS, and C-KIT genes were found in the analyzed population. This indicates that environmental and genetic factors significantly influence the introduction of the disease in this geographic region.

Keyphrases

genome wide
wild type
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
dna methylation
bioinformatics analysis
patient reported outcomes
gene expression
climate change