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Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience.

Jana Käthe StrieflerFranziska BrandesAlexander BaurBerit Maria PfitznerDavid KaulDaniel RauAnne DörrMaren SchmiesterGeorgios KoulaxouzidisLars BullingerSven MärdianAnne Flörcken
Published in: BMC cancer (2020)
This single-centre experience does also not support the promising phase Ib/II results for olaratumab/doxorubicin in STS. However, our findings do not preclude that olaratumab combination therapy could be valuable in a neoadjuvant setting. This warrants further exploration also taking into account the heterogeneous nature of STS.
Keyphrases
  • combination therapy
  • drug delivery
  • cancer therapy
  • squamous cell carcinoma
  • rectal cancer
  • small cell lung cancer
  • lymph node
  • locally advanced