Curcuminoid Chalcones: Synthesis and Biological Activity against the Human Colon Carcinoma (Caco-2) Cell Line.

Dorota Olender Katarzyna Sowa-Kasprzak Anna Pawełczyk Bartosz Skóra Lucjusz Zaprutko Konrad A Szychowski

Published in: Current medicinal chemistry (2023)

The results suggested that compound 3a increased the metabolism and/or proliferation of the human colon carcinoma (Caco-2) cell line, while compounds 3b and 3f showed significant toxicity against the Caco-2 cell line. Overall, the preliminary results suggested that compound 3b exhibited the most favorable anticancer activity.

Keyphrases

endothelial cells
induced pluripotent stem cells
oxidative stress