HBV vaccination and HBV infection induces HBV-specific natural killer cell memory.
Ratna S WijayaScott A ReadNaomi R TruongShuanglin HanDishen ChenHaleh ShahidipourNicole L FewingsStephen SchibeciMahmoud K AzardaryanyGrant P ParnellDavid BoothDavid van der PoortenRita LinJacob GeorgeMark W DouglasGolo AhlenstielPublished in: Gut (2020)
Our data support the presence of a mature mNKs following HBV antigen exposure either through vaccination or infection. Harnessing these antigen specific, functionally active mNKs provides an opportunity to develop novel treatments targeting HBV in chronic infection.