An exploratory analysis of clinical and sociodemographic factors in CGRP-induced migraine attacks: A REFORM study.
Haidar M Al-KhazaliHåkan AshinaRune Häckert ChristensenAstrid WiggersKathrine RoseAfrim IljaziHenrik Winther SchytzFaisal Mohammad AminMessoud AshinaPublished in: Cephalalgia : an international journal of headache (2023)
Our results suggest that cutaneous allodynia and aura play a role in CGRP-induced migraine attacks, while other clinical and sociodemographic factors do not seem to have any noticeable impact. This indicates that the CGRP provocation model is robust, as the CGRP hypersensitivity remained unaffected despite differences among a heterogeneous migraine population.Trial Registration: ClinicalTrials.gov Identifier: NCT04592952.