Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression.

Pit Shan ChongChi Him PoonJaydeep RoyKa Chun TsuiSze Yuen LewMichael Weng Lok PhangRachael Julia Yuenyinn TanPoh Guat ChengMan-Lung FungKah Hui WongLee-Wei Lim

Published in: Chinese medicine (2021)

HE exerts antidepressant effects by promoting neurogenesis and reducing neuroinflammation through enhancing the BDNF-TrkB-CREB signalling pathway.

Keyphrases

major depressive disorder
cerebral ischemia
neural stem cells
depressive symptoms
traumatic brain injury
lipopolysaccharide induced
subarachnoid hemorrhage
bipolar disorder
brain injury
blood brain barrier
stress induced
sleep quality
cognitive impairment
physical activity