Role of embryonic origin on osteogenic potential and bone repair capacity of rat calvarial osteoblasts.

Alann Thaffarell Portilho SouzaHelena Bacha LopesGileade Pereira FreitasEmanuela Prado FerrazFabiola Singaretti OliveiraAdriana Luisa Gonçalves AlmeidaDenise WeffortMarcio Mateus BelotiAdalberto Luiz Rosa

Published in: Journal of bone and mineral metabolism (2020)

Despite the distinct in vitro osteogenic potential, OB-NC and OB-MS induced similar bone repair in a rat calvarial defect model. Thus, osteoblasts, irrespective of their in vitro osteogenic potential linked to embryonic origins, seem to be suitable for cell-based therapies aiming to repair bone defects.

Keyphrases

bone regeneration
mesenchymal stem cells
bone marrow
bone mineral density
oxidative stress
human health
bone loss
multiple sclerosis
mass spectrometry
cell therapy
single cell
ms ms
high glucose
diabetic rats
endothelial cells
drug induced
stress induced