Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain.

Thomas AmortDietmar RiederAlexandra WilleDaria Khokhlova-CubberleyChristian RimlLukas TrixlXi-Yu JiaRonald MicuraAlexandra Lusser

Published in: Genome biology (2017)

Our study presents the first comprehensive picture of cytosine methylation in the epitranscriptome of pluripotent and differentiated stages in the mouse. These data provide an invaluable resource for future studies of function and biological significance of m5C in mRNA in mammals.

Keyphrases

embryonic stem cells
electronic health record
dna methylation
resting state
white matter
genome wide
machine learning
functional connectivity
data analysis