Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain.
Thomas AmortDietmar RiederAlexandra WilleDaria Khokhlova-CubberleyChristian RimlLukas TrixlXi-Yu JiaRonald MicuraAlexandra LusserPublished in: Genome biology (2017)
Our study presents the first comprehensive picture of cytosine methylation in the epitranscriptome of pluripotent and differentiated stages in the mouse. These data provide an invaluable resource for future studies of function and biological significance of m5C in mRNA in mammals.